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Item number674041
Molecular weight154,21 g/mol
Quantity 1x1000mg
storage conditions20 °C


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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 21.04.2021
Product name:Biphenyl
Catalog No.:674041
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf

Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Skin irritation (Category 2)
Eye irritation (Category 2)
Specific target organ toxicity - single exposure (Category 3)
Acute aquatic toxicity (Category 1)
Chronic aquatic toxicity (Category 1)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Irritating to eyes, respiratory system and skin. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
Label elements
PictogramGHS07 exclam
GHS09 Aquatic-pollut-red
Signal word Warning
Hazard statement(s)
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P261 Avoid breathing dust. P273 Avoid release to the environment.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P501 Dispose of contents/ container to an approved waste disposal plant.
Supplemental Hazard
None R-phrase(s)
R36/37/38 Irritating to eyes, respiratory system and skin.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S23 Do not breathe gas/fumes/vapour/spray.
S60 This material and its container must be disposed of as hazardous waste.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
2.3 Other hazards - none
Formula : C12H10
Molecular Weight : 154,21 g/mol
Component Concentration
Molecular Weight (g/mol)154.21
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
Liver injury may occur., Gastrointestinal disturbance
4.3 Indication of any immediate medical attention and special treatment needed
no data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s)
no data available
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry Hands The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Fluorinated rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
Splash protection
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 30 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail,
test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an Industrial Hygienist familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
Use respirators and components tested and approved under appropriate government standards
such as NIOSH (US) or CEN (EU).
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline
Colour: light yellow
b) Odour characteristic
c) Odour Threshold no data available
d) pH 5,5
e) Melting point/freezing
Melting point/range: 68 - 70 °C - lit.
f) Initial boiling point and
boiling range
255 °C - lit.
g) Flash point 110 °C - closed cup
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower
flammability or
explosive limits
Upper explosion limit: 5,8 %(V)
Lower explosion limit: 0,6 %(V)
k) Vapour pressure 0,04 hPa at 20 °C
5,5 hPa at 100 °C
12,6 hPa at 115 °C
95,7 hPa at 166 °C
l) Vapour density no data available
m) Relative density 0,992 g/cm3
n) Water solubility 0,0075 g/l at 15 °C o) Partition coefficient: noctanol/
no data available
p) Auto-ignition
no data available
q) Decomposition
no data available
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
9.2 Other safety information
no data available
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Other decomposition products - no data available
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - rat - 2.140 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Behavioral:Muscle weakness.
Gastrointestinal disturbance
Inhalation: no data available
LD50 Dermal - rabbit - > 5.010 mg/kg
Skin corrosion/irritation
Skin - rabbit - Irritating to skin. - 24 h - Draize Test
Serious eye damage/eye irritation
Eyes - rabbit - Mild eye irritation - Draize Test
Respiratory or skin sensitization
guinea pig -
Remarks: Did not cause sensitization on laboratory animals.
Germ cell mutagenicity
Genotoxicity in vitro - mouse - lymphocyte
DNA damage
Genotoxicity in vitro - mouse - lymphocyte
Mutation in mammalian somatic cells.
Genotoxicity in vitro - Hamster - Lungs
Mutation in microorganisms Genotoxicity in vitro - Hamster - fibroblast
Sister chromatid exchange
Genotoxicity in vivo - rat - Oral
Unscheduled DNA synthesis
Genotoxicity in vivo - mouse - Oral
DNA damage
Carcinogenicity - mouse - Oral
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Lungs, Thorax, or Respiration:Tumors.
Carcinogenicity - mouse - Subcutaneous
Tumorigenic:Neoplastic by RTECS criteria. Lungs, Thorax, or Respiration:Tumors. Liver:Tumors.
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard no data available
Potential health effects
Inhalation May be harmful if inhaled. Causes respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. Causes skin irritation.
Eyes Causes serious eye irritation.
Signs and Symptoms of Exposure
Liver injury may occur., Gastrointestinal disturbance
Additional Information
RTECS: DU8050000
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 1,45 mg/l - 96,0 h
LC0 - Danio rerio (zebra fish) - 38 mg/l - 96,0 h
LC50 - Salmo gairdneri - 1,5 mg/l - 96,0 h
LC50 - Lepomis macrochirus (Bluegill) - 4,7 mg/l - 96,0 h
Toxicity to daphnia and
other aquatic
LC50 - Daphnia magna (Water flea) - 0,36 mg/l - 48 h
12.2 Persistence and degradability
Biodegradability Method: Closed Bottle test
Remarks: According to the results of tests of biodegradability this product is
considered as being readily biodegradable.
12.3 Bioaccumulative potential
Bioaccumulation Leuciscus idus (Golden orfe) - 3 d -50 μg/l
Bioconcentration factor (BCF): 281 12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
Very toxic to aquatic life.
no data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
ADR/RID: 3077 IMDG: 3077 IATA: 3077
14.2 UN proper shipping name
IATA: Environmentally hazardous substance, solid, n.o.s. (Biphenyl)
14.3 Transport hazard class(es)
14.4 Packaging group
14.5 Environmental hazards
ADR/RID: yes IMDG Marine Pollutant: yes IATA: yes
14.6 Special precautions for user
no data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!