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Captopril

Item number689581
CAS62571-86-2
FormulaC9H15NO3S
Molecular weight217,29 g/mol
Quantity 1X250MG
storage conditions4 °C
CoA / MSDSRetrieve CoA
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Captopril

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Captopril

Captopril

689581
62571-86-2

1X250MG

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Captopril solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

Captopril solution

689582
62571-86-2

1X5ML

On request

Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 09.05.2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Captopril
Catalog No.:689581
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION· 2.1 Classification of the substance or mixture
· Classification according to Regulation (EC) No 1272/2008
health hazard
Repr. 1A H360D May damage the unborn child.
Skin Sens. 1 H317 May cause an allergic skin reaction.
Label elements
PictogramGHS07 exclam
exclam
GHS08 silhouete
silhouete
· 2.2 Label elements
· Labelling according to Regulation (EC) No 1272/2008
The substance is classified and labelled according to the CLP regulation
· Hazard pictograms
GHS07 GHS08
· Signal word Danger
· Hazard statements
H317 May cause an allergic skin reaction.
H360D May damage the unborn child.
· Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P321 Specific treatment (see on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international
regulations.
· Additional information:
Restricted to professional users.
· 2.3 Other hazards
· Results of PBT and vPvB assessment
· PBT: Not applicable.
· vPvB: Not applicable.
COMPOSITION/INFORMATION ON INGREDIENTS· 3.1 Chemical characterisation: Substances
· CAS No. Description
62571-86-2 Captopril
· Identification number(s) None
· EC number: 263-607-1
· RTECS: UY0550000
· Additional information: For the wording of the listed hazard phrases refer to section 16.
FormulaC9H15NO3S
Molecular Weight (g/mol)217.29
CAS-No.62571-86-2
FIRST AID MEASURES· 4.1 Description of first aid measures
· After inhalation:
Supply fresh air and call a doctor.
In case of unconsciousness place patient in recovery position for transport.
· After skin contact: Immediately wash with water and soap and rinse thoroughly.
· After eye contact: Rinse opened eye for several minutes under running water.
· After swallowing: Rinse mouth. Do not induce vomiting.
· 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available
4.3 Indication of any immediate medical attention and special treatment needed
No further relevant information available.
FIRE-FIGHTING MEASURES· 5.1 Extinguishing media
· Suitable extinguishing agents: Use fire extinguishing methods suitable for surrounding conditions.
· 5.2 Special hazards arising from the substance or mixture
Formation of toxic gases is possible during heating or in case of fire.
· 5.3 Advice for firefighters
· Protective equipment: Wear self-contained respiratory protective device.
ACCIDENTAL RELEASE MEASURES· 6.1 Personal precautions, protective equipment and emergency procedures Avoid formation of dust.
· 6.2 Environmental precautions: Do not allow to enter sewers/ surface or ground water.
· 6.3 Methods and material for containment and cleaning up:
Dispose of contaminated material as waste according to item 13.
· 6.4 Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
HANDLING AND STORAGE· 7.1 Precautions for safe handling Store in cool, dry place in tightly closed receptacles.
· Information about fire - and explosion protection: No special measures required.
· 7.2 Conditions for safe storage, including any incompatibilities
· Storage:
· Requirements to be met by storerooms and receptacles:
Please refer to the manufacturers certificate for specific storage and transport temperature conditions.
Store only in the original receptacle unless other advice is given on the CoA.
Keep container in a well-ventilated place. Keep away from sources of ignition and heat.
· Information about storage in one common storage facility: Store away from foodstuffs.
· Further information about storage conditions: None.
· 7.3 Specific end use(s) No further relevant information available
EXPOSURE CONTROLS/PERSONAL PROTECTION· 8.1 Control parameters
· Additional information about design of technical facilities: No further data; see item 7.
· Ingredients with limit values that require monitoring at the workplace: Not required.
· Additional information: Lists used were valid at the time of SDS preparation.
· 8.2 Exposure controls
· Personal protective equipment:
· General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
· Respiratory protection:
Not required.
Use suitable respiratory protective device in case of insufficient ventilation.
· Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the
degradation
The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the
related standard EN374
Protective gloves
· Material of gloves Butyl rubber, BR
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be
observed.
· Eye protection: Safety glasses
PHYSICAL AND CHEMICAL PROPERTIES· 9.1 Information on basic physical and chemical properties
· General Information
· Appearance:
Form: Crystalline powder
Colour: White
· Odour: Sulfurous
· Odour threshold: Not determined.
· pH-value: Not applicable.
· Change in condition
Melting point/freezing point: 105-110 °C
Initial boiling point and boiling range: 427 °C
· Flash point: 212 °C
· Flammability (solid, gas): Not determined.
· Ignition temperature: Not determined
· Decomposition temperature: Not determined.
· Auto-ignition temperature: Not determined.
· Explosive properties: Not determined.
· Explosion limits:
Lower: Not determined.
Upper: Not determined.
· Vapour pressure: Not applicable.
· Density at 20 °C: 1.272 g/cm³
· Relative density Not determined.
· Vapour density Not applicable.
· Evaporation rate Not applicable.
· Solubility in / Miscibility with Dichloromethane, Ethanol, Methanol
· water at 20 °C: 0.1 g/l
· Partition coefficient: n-octanol/water: 0.34 logP
· Viscosity:
Dynamic: Not applicable.
Kinematic: Not applicable.
· 9.2 Other information No further relevant information available.
STABILITY AND REACTIVITY· 10.1 Reactivity
Stable under normal conditions.
No further relevant information available.
· 10.2 Chemical stability Stable under normal conditions.
· Thermal decomposition / conditions to be avoided:
Formation of toxic gases is possible during heating or in case of fire.
· 10.3 Possibility of hazardous reactions No dangerous reactions known.
· 10.4 Conditions to avoid Heat.
· 10.5 Incompatible materials: Strong oxidizing agents.
· 10.6 Hazardous decomposition products:
Formation of toxic gases is possible during heating or in case of fire.
TOXICOLOGICAL INFORMATION· 11.1 Information on toxicological effects
· Acute toxicity Based on available data, the classification criteria are not met.
· LD/LC50 values relevant for classification:
Oral LD50 2,078 mg/kg (mouse)
4,245 mg/kg (rat)
LD 50 (Intravenous) 554 mg/kg (rat)
· Primary irritant effect:
· Skin corrosion/irritation Based on available data, the classification criteria are not met.
· Serious eye damage/irritation Based on available data, the classifcation criteria are not met.
· Respiratory or skin sensitisation
May cause an allergic skin reaction.
· Additional toxicological information:
· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)
Oral Reproductive 100 mg/kg (rat) (female 6-15 day(s) after conception)
40 mg/kg (rabbit) (female 15-30 day(s) after conception)
Repr. 1A
· Germ cell mutagenicity Based on available data, the classification criteria are not met.
· Carcinogenicity Based on available data, the classification criteria are not met.
· Reproductive toxicity
May damage the unborn child.
· STOT-single exposure Based on available data, the classification criteria are not met.
· STOT-repeated exposure Based on available data, the classification criteria are not met.
· Aspiration hazard Based on available data, the classification criteria are not met.
ECOLOGICAL INFORMATION· 12.1 Toxicity
· Aquatic toxicity: No further relevant information available.
· 12.2 Persistence and degradability Not readily biodegradable: 15% biodegradation in 28 days.
· 12.3 Bioaccumulative potential No further relevant information available.
· 12.4 Mobility in soil No further relevant information available.
· Additional ecological information:
· General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water
Do not allow undiluted product to reach ground water, water course or sewage system.
· 12.5 Results of PBT and vPvB assessment
· PBT: Not applicable.
· vPvB: Not applicable.
· 12.6 Other adverse effects No further relevant information available.
DISPOSAL CONSIDERATIONS· 13.1 Waste treatment methods
· Recommendation
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· Uncleaned packaging:
· Recommendation: Dispose of in accordance with national regulations.
TRANSPORT INFORMATION· 14.1 UN-Number
· ADR, IMDG, IATA Not applicable
· ADR, IMDG, IATA Not applicable
· 14.3 Transport hazard class(es)
· ADR, ADN, IMDG, IATA
· Class Not applicable
· 14.4 Packing group
· ADR, IMDG, IATA Not applicable
· 14.5 Environmental hazards: Not applicable.
· 14.6 Special precautions for user Not applicable.
· 14.7 Transport in bulk according to Annex II of
Marpol and the IBC Code Not applicable.
· UN "Model Regulation": Not applicable
REGULATORY INFORMATION· 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
· Directive 2012/18/EU
· Named dangerous substances - ANNEX I Substance is not listed.
· 15.2 Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!