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Colistin sulfate

Item number672951
CAS1264-72-8
Quantity 1X100MG
storage conditions4 °C
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Colistin sulfate

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 29.03.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Colistin sulfate
Catalog No.:672951
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION· 2.1 Classification of the substance or mixture
· Classification according to Regulation (EC) No 1272/2008
GHS06 skull and crossbones
Acute Tox. 3 H301 Toxic if swallowed.
Label elements
PictogramGHS06 skull
skull
· 2.2 Label elements
· Labelling according to Regulation (EC) No 1272/2008
The substance is classified and labelled according to the CLP regulation.
· Hazard pictograms
GHS06
· Signal word Danger
· Hazard statements
H301 Toxic if swallowed.
· Precautionary statements
P264 Wash thoroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.
P321 Specific treatment (see on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international
regulations.
· 2.3 Other hazards
· Results of PBT and vPvB assessment
· PBT: Not applicable.
· vPvB: Not applicable.
COMPOSITION/INFORMATION ON INGREDIENTS· 3.1 Chemical characterisation: Substances
· CAS No. Description
1264-72-8 Colistin sulfate
· Identification number(s) None
· EC number: 215-034-3
· RTECS: TR1500000
· Additional information: For the wording of the listed hazard phrases refer to section 16.
Formula
Molecular Weight (g/mol)0.00
CAS-No.1264-72-8
FIRST AID MEASURES· 4.1 Description of first aid measures
· General information:
Immediately remove any clothing soiled by the product.
In case of irregular breathing or respiratory arrest provide artificial respiration.
· After inhalation: Supply fresh air; consult doctor in case of complaints.
· After skin contact: Immediately wash with water and soap and rinse thoroughly.
· After eye contact: Rinse opened eye for several minutes under running water. Then consult a doctor.
· After swallowing:
Rinse mouth. Do not induce vomiting.
Call for a doctor immediately.
· 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available.
· 4.3 Indication of any immediate medical attention and special treatment needed
No further relevant information available.
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Sulphur oxides, Tungsten oxide
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: 2 - 8 °C
7.3 Specific end uses
no data available
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
PHYSICAL AND CHEMICAL PROPERTIES· 9.1 Information on basic physical and chemical properties
· General Information
· Appearance:
Form: Solid
Colour: Off white
· Odour: Odourless
· Odour threshold: Not determined.
· pH-value: Not applicable.
· Change in condition
Melting point/freezing point: Not determined.
Initial boiling point and boiling range: 1,537 °C
· Flash point: 883 °C
· Flammability (solid, gas): Not determined.
· Ignition temperature: Not determined
· Decomposition temperature: Not determined.
· Auto-ignition temperature: Not determined.
· Explosive properties: Not determined.
· Explosion limits:
Lower: Not determined.
Upper: Not determined.
· Vapour pressure: Not applicable.
· Density: Not determined
· Relative density Not determined.
· Vapour density Not applicable.
· Evaporation rate Not applicable.
· Solubility in / Miscibility with
water at 20 °C: 5.64 g/l
· Partition coefficient: n-octanol/water: -2.4 Log P
· Viscosity:
Dynamic: Not applicable.
Kinematic: Not applicable.
· 9.2 Other information No further relevant information available.
STABILITY AND REACTIVITY10.1 Reactivity
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Oxidizing agents, Strong acids
10.6 Hazardous decomposition products
Other decomposition products - no data available
TOXICOLOGICAL INFORMATION· 11.1 Information on toxicological effects
· Acute toxicity
Toxic if swallowed.
· LD/LC50 values relevant for classification:
Oral LD50 121 mg/kg (rat)
LD 50 (Intraperitoneal) 10.6 mg/kg (rat)
LD 50 (Intravenous) 5.5 mg/kg (mouse)
· Primary irritant effect:
· Skin corrosion/irritation Based on available data, the classification criteria are not met.
· Serious eye damage/irritation Based on available data, the classification criteria are not met.
· Respiratory or skin sensitisation Based on available data, the classification criteria are not met.
· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)
· Germ cell mutagenicity Based on available data, the classification criteria are not met.
· Carcinogenicity Based on available data, the classification criteria are not met.
· Reproductive toxicity Based on available data, the classification criteria are not met.
· STOT-single exposure Based on available data, the classification criteria are not met.
· STOT-repeated exposure Based on available data, the classification criteria are not met.
· Aspiration hazard Based on available data, the classification criteria are not met.
ECOLOGICAL INFORMATION12.1 Toxicity
no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
no data available
DISPOSAL CONSIDERATIONS· 13.1 Waste treatment methods
· Recommendation
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· European waste catalogue
Waste disposal key numbers from EWC have to be assigned depending on origin and processing.
· Uncleaned packaging:
· Recommendation: Dispose of in accordance with national regulations.
· Recommended cleansing agents: Water, if necessary together with cleansing agents.
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 2811 IMDG: 2811 IATA: 2811
14.2 UN proper shipping name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (Colistin sulfate salt)
IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Colistin sulfate salt)
IATA: Toxic solid, organic, n.o.s. (Colistin sulfate salt)
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
no data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!