Phenylbutazone

Ensure Accurate Residue Analysis with High-Purity Phenylbutazone Reference Materials

HPC Standards GmbH offers top-tier Phenylbutazone reference materials, meticulously tested to meet international quality standards. Essential for laboratories in food and environmental analysis, our high-purity products guarantee precise and reliable results, ensuring compliance with regulatory limits. Trust HPC Standards as your competent partner in delivering excellence in residue analysis.

Product	Catalog No./ CAS No.	Quantity	Price
13C12-Phenylbutazone	679675 1325559-13-4	1X10MG	Please log in.
13C12-Phenylbutazone solution Concentration: 100 µg/ml Solvent: Acetonitrile	690911 1325559-13-4	1X1ML	On request
D10-Phenylbutazone	674808 1219794-69-0	1X10MG	Please log in.
Phenylbutazone	681358 50-33-9	1X100MG	Please log in.

High-purity reference materials for accurate and reliable residue analysis.

Overview

Phenylbutazone, also known as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the treatment of pain and fever in animals. It is not approved for human use in the United States and United Kingdom, except for specific conditions in the UK.

Uses

In Humans: Initially used for rheumatoid arthritis and gout, it is now restricted to treating ankylosing spondylitis in the UK when other therapies are unsuitable.

In Horses: Commonly used for pain relief from infections and musculoskeletal disorders, including sprains, tendinitis, arthritis, and laminitis. It also reduces fevers.

In Dogs: Occasionally used for managing chronic pain, particularly osteoarthritis, though other NSAIDs are more commonly preferred.

Regulatory

Phenylbutazone is a prescription-only medication. Its use in horses is limited to those not intended for food, due to the risk of aplastic anemia in humans from its metabolites.

Monitoring

Regular blood work and renal monitoring are recommended for animals receiving chronic phenylbutazone therapy. Special care is needed for young, ill, or stressed animals.

Health Impact

Human Toxicity

Phenylbutazone can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. It is no longer approved for human use in the US due to these risks.

Environmental Impact

Effects on Wildlife

Phenylbutazone metabolites can cause aplastic anemia in humans, raising concerns about its environmental impact when used in animals.

Safety Measures

Phenylbutazone should be administered orally or intravenously. It should not be given intramuscularly or injected in any place other than a vein to avoid tissue damage. Regular monitoring is essential to prevent overdose and prolonged use complications.

Analytical Standards

HPC Standards GmbH provides high-purity reference materials for Phenylbutazone, ensuring accurate and reliable residue analysis. Our products are tested according to international quality requirements and meet the highest industrial standards.