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Chlorthalidone Reference Materials

High-Purity Chlorthalidone Reference Materials for Accurate Residue Analysis

Ensure precision in your residue analysis with HPC Standards GmbHs high-purity Chlorthalidone reference materials. Our products meet international quality requirements and the highest industrial standards, making them essential for laboratories conducting food and environmental analysis. Trust HPC Standards GmbH for reliable and compliant analytical solutions.

Product

Catalog No./ CAS No.

Quantity

Price

Chlorthalidone

Chlorthalidone

691867
77-36-1

1X10MG

On request

Chlorthalidone solution
Concentration: 100 µg/ml
Solvent: Water

Chlorthalidone solution

691911
77-36-1

1X1ML

On request

D4-Chlorthalidone

D4-Chlorthalidone

691136
1794941-44-8

1X5MG

On request

D4-Chlorthalidone solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

D4-Chlorthalidone solution

691138
1794941-44-8

1X1ML

On request

High-purity reference materials for accurate residue analysis

Overview

Chlorthalidone is a thiazide-like diuretic drug used to treat high blood pressure, swelling, diabetes insipidus, and renal tubular acidosis. It is effective in most patients with high blood pressure and is considered a preferred initial treatment. It is also used to prevent calcium-based kidney stones.

Chlorthalidone is taken by mouth, with effects generally beginning within three hours and lasting up to three days. Long-term treatment with chlorthalidone is more effective than hydrochlorothiazide for preventing heart attack or stroke.

Uses

Chlorthalidone is used for:

  • Treating high blood pressure
  • Reducing swelling (edema)
  • Preventing calcium-based kidney stones
  • Treating left ventricular hypertrophy
  • Managing diabetes insipidus
  • Preventing bone fractures
  • Treating Ménière's disease

Regulatory

Chlorthalidone is approved for use by prescription only in the UK and the US. It is on the World Health Organization's List of Essential Medicines and is available as a generic medication.

Monitoring

Regular monitoring of blood pressure, electrolyte levels, and kidney function is recommended during chlorthalidone treatment. Monitoring helps in managing potential side effects and ensuring the effectiveness of the treatment.

Health Impact

Human toxicity

Common adverse effects include low blood potassium, low blood sodium, high blood sugar, dizziness, and erectile dysfunction. Other adverse effects may include gout, low blood magnesium, high blood calcium, allergic reactions, and low blood pressure. The risk of adverse effects is higher in persons with diabetes mellitus and those with low dietary magnesium intake.

Environmental Impact

Effects on wildlife

Chlorthalidone can potentially impact aquatic life if it enters water bodies through pharmaceutical waste. Proper disposal and environmental monitoring are essential to mitigate these effects.

Safety Measures

Safety measures include regular monitoring of electrolyte levels, kidney function, and blood pressure. Patients should be educated on the importance of adhering to prescribed dosages and reporting any adverse effects to their healthcare provider.

Regulation

Chlorthalidone is regulated as a prescription-only medication in many countries. It is banned in some sports due to its diuretic properties, which can be used to reduce body weight or mask the use of performance-enhancing drugs.

Analytical Standards

HPC Standards GmbH provides high-purity reference materials for chlorthalidone, ensuring accurate and reliable residue analysis. Our products meet international quality requirements and the highest industrial standards. These reference materials are essential for laboratories conducting food and environmental analysis to ensure compliance with regulatory limits.