Benzyldimethyldodecylammonium chloride (C12 benzalkonium chloride) – Reference Materials

Benzyldimethyldodecylammonium chloride2 Precision Reference Materials for Confident BAC Residue Analysis

Elevate your LC-MSMS workflows with high-purity, well-characterized reference materials for benzyldimethyldodecylammonium chloride C12 BAC. HPC Standards delivers traceable single-component solutions and homolog mixes designed for accurate calibration, matrixmatched validation, and proficiency testing across food, environmental, and industrial hygiene applications. Each lot ships with a comprehensive CoA identity, concentration, uncertainty, expiry and meets international quality requirements. Benefit from optimized formats for reversed-phaseHILIC methods, isotopically supported quantification, and custom concentrations or BAC series mixes on requestso your lab can meet regulatory limits with confidence and repeatability.

Product		Catalog No./ CAS No.	Quantity	Price
Benzyldimethyltetradecylammonium chloride solution Concentration: 10.0 µg/ml Solvent: Acetonitrile		674529 139-08-2	1X10ML	Please log in.
Benzyldimethyltetradecylammonium chloride solution Concentration: 100 µg/ml Solvent: Acetonitrile		678116 139-08-2	1X10ML	Please log in.

High-quality reference materials for precise determination of benzyl-dimethyl-dodecylammonium chloride (C12 BAC) in food, environmental, and industrial matrices.

Overview

Benzyldimethyldodecylammonium chloride (also: dodecylbenzyldimethylammonium chloride, C12 benzalkonium chloride, BDDAC) is a cationic quaternary ammonium compound (QAC) widely used as a disinfectant, sanitizer, and preservative. It is one homolog within the benzalkonium chloride (BAC) group, defined by an alkyl chain length distribution (commonly C12–C18).

Due to broad antimicrobial efficacy, residues may occur on food-contact surfaces, in food commodities, and in environmental compartments. Accurate quantification requires well-characterized reference materials.

Chemical Identity

Chemical class: quaternary ammonium compound (cationic surfactant).

IUPAC/Name: benzyldimethyldodecylammonium chloride; synonyms include BDDAC, C12 BAC.

General formula (BAC homolog): [C6H5CH2N(CH3)2R]+Cl− with R = C12H25 for this homolog. High water solubility; strong adsorption to negatively charged surfaces and particulates.

Uses

Applied as disinfectant and sanitizer in healthcare, food-processing, domestic cleaners, and cosmetics; acts as preservative and antistatic/biocidal agent in industrial formulations.

Often present as mixtures of homologs (C12, C14, C16, C18); C12 is among the predominant and analytically critical components.

Regulatory

Subject to biocidal product regulations (region-specific; e.g., EU Biocidal Products Regulation for relevant product types). Residue limits for QACs (including BAC) in food and on food-contact materials are defined by regional authorities; monitoring programs frequently address the sum of BAC homologs.

Workplace safety classification and labeling follow chemical safety frameworks (e.g., CLP/GHS) for skin/eye irritation and aquatic toxicity. Always consult current jurisdictional limits and guidance.

Monitoring and Analytical Methods

Preferred techniques: LC-MS/MS in positive ESI with reversed-phase or HILIC separations. Separation of individual BAC homologs (C12, C14, C16, etc.) is recommended for profiling; quantification may be reported per homolog and/or as sum of BACs.

Sample preparation: solid-phase extraction (cation-exchange or mixed-mode) or protein precipitation for complex matrices; avoid glass where possible due to cationic adsorption. Add organic modifiers (e.g., low % FA or ammonium formate) to reduce adsorption and improve peak shape.

Quality control: use matrix-matched calibration; apply isotopically labelled internal standards where available to correct for ion suppression and recovery. Employ procedural blanks and fortified matrix controls.

Health Impact

Human toxicity: Cationic surfactant with irritant/corrosive potential to skin and eyes at higher concentrations; may cause respiratory irritation via aerosols. Acute oral toxicity is moderate; systemic absorption is generally limited but formulation and concentration influence hazard. Follow safety data sheet guidance.

Environmental Impact

Cationic charge drives strong sorption to soils, sediments, and sludge; limited mobility in water but persistence on solids can be relevant. Toxic to aquatic organisms, particularly at low mg/L to sub‑mg/L ranges depending on species and conditions. Biodegradation is variable and influenced by environmental matrices.

Effects on wildlife: Potential membrane-disrupting effects typical for surfactants; risk is higher in benthic compartments where sorbed fractions accumulate.

Safety Measures

Use PPE: lab coat, nitrile gloves, eye protection; handle solutions in a fume hood to avoid aerosol exposure. Avoid contact with anionic surfactants and strong oxidants. In case of spills, absorb with inert material; prevent release to drains.

First aid: rinse affected skin/eyes with water; seek medical advice for persistent irritation. Refer to SDS for full instructions.

Fate and Transport

Strong adsorption to organic matter and negatively charged surfaces; reduced volatility; primary removal via sludge in wastewater treatment. Photolysis and biodegradation depend on conditions; transformation products may form.

Matrix Applications

Common matrices: surface rinses and swabs (food-contact), beverages, dairy, produce, cosmetics, wastewater, surface water, sludge, soils, and wipes. Validate extraction efficiency in each matrix due to strong sorption and matrix effects.

Analytical Challenges

Ion suppression in ESI from salts and lipids; carryover due to adsorption to tubing and column hardware; homolog coelution and in-source fragmentation can bias results. Use PEEK-lined flow paths, dedicated wash solvents, and stable isotope internal standards where possible.

Analytical Standards

HPC Standards provides certified reference materials for benzyldimethyldodecylammonium chloride (C12 BAC) as single-component solutions or as part of BAC homolog mixes. Materials are tested according to international quality requirements to meet high industrial standards and ensure metrological traceability.

Concentrations, solvents, and uncertainty data are supplied with comprehensive documentation to support method validation, calibration, and proficiency testing.

Storage and Stability

Store sealed at 2–8 °C, protected from light. Avoid contact with glass and anionic contaminants. Allow to equilibrate to room temperature before opening to minimize condensation. Observe shelf life stated on the certificate.

Documentation and Traceability

Each product is delivered with a certificate of analysis including identity confirmation, concentration, uncertainty, and expiry. Batch-specific traceability and reference to measurement procedures enable reliable, auditable results.

Packaging and Formats

Available as neat material (where applicable) and as ready-to-use solutions in suitable solvents and concentrations for LC-MS workflows. Custom concentrations, multi-analyte mixes (BAC homolog series), and matrix-matched solutions are available on request.

Regulatory Compliance Support

Our reference materials support compliance monitoring for BAC residues in food, environmental, and industrial hygiene programs in line with regional regulations and guidance. Contact our technical team for region-specific method and reporting support.

Ordering Information

Products are intended for professional laboratory use. For quotes, availability, and custom mixtures, please provide target concentration, solvent, volume, and required homolog composition.