New user? / Forgot your password?
0 Item | 0,00 €
Methylpyrene – Reference Materials for Environmental and Industrial Analysis
Methylpyrene Precision Reference Materials for Confident PAH Analysis
Unlock consistent, defensible results with HPC Standards high-purity Methylpyrene isomer standards. Our certified neat materials and ready-to-use solutions enable isomer-resolved calibration, system suitability, and QAQC across GCLC methodsessential for source apportionment, environmental monitoring, and industrial hygiene. Benefit from isotopelabelled options, tailored PAHmethylPAH mixes, and comprehensive CoAs detailing identity, purity, uncertainty, and traceability. Rely on proven lot-to-lot consistency, expert technical support, and products tested to international quality requirements for streamlined compliance and method validation.
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 683700 | 1X100MG | Please log in. | |
ISO 17034 Certified Reference Material 1-Methylpyrene solution |  | 684893 | 1X10ML | Please log in. |
1-Methylpyrene solution |  | 694213 | 1X5ML | Please log in. |
High-purity reference materials for methylated pyrene isomers to support precise identification, quantification, and compliance in environmental monitoring and industrial quality control.
Overview
Methylpyrenes are alkylated polycyclic aromatic hydrocarbons (PAHs) derived from pyrene with one methyl substituent. Multiple positional isomers exist (e.g., 1-, 2-, 3-, 4-methylpyrene), each with distinct physicochemical and chromatographic behavior but similar PAH core properties such as hydrophobicity, low volatility, and persistence.
They occur as components of petroleum-derived mixtures and as by-products of incomplete combustion. In analytical chemistry, methylpyrenes serve as target compounds and markers in source apportionment studies and environmental fate assessments.
Chemical Identity and Isomerism
- Chemical class: Alkylated PAHs (C17H12 for mono-methylpyrene isomers).
- Structural diversity: Positional isomers (1-, 2-, 3-, 4-methylpyrene) differ in chromatographic retention and fluorescence/emission profiles, requiring isomer-resolved methods.
- Properties: High logKow (strong hydrophobicity), low aqueous solubility, strong sorption to black carbon and organic matter; fluorescence-active.
Isomer differentiation is critical for source attribution and accurate quantification in complex matrices containing multiple PAHs and alkyl-PAH homologues.
Sources and Uses
- Formation: Pyrolysis and combustion of organic material (fossil fuels, biomass), vehicular and industrial emissions, wildfires; presence in crude oil and refined petroleum products.
- Uses: Research chemicals for environmental forensics, method development, and instrument calibration; components in complex reference mixtures for PAH profiling.
Methylpyrenes are not typically manufactured for end-use products; they are analyzed as contaminants or as diagnostic markers in environmental and industrial hygiene contexts.
Regulatory Landscape
- PAH regulations commonly target priority parent PAHs (e.g., EPA-16) and food-related PAH4/PAH8 groups; methylated PAHs, including methylpyrenes, may be monitored as part of extended PAH suites for risk assessment and source apportionment.
- Air, water, soil, and waste regulations can require PAH surveillance; inclusion of alkylated PAHs is jurisdiction- and method-dependent.
Users should verify applicable local and sector-specific requirements (environmental permits, occupational air monitoring, product stewardship) and document method performance for methylated congeners.
Monitoring and Analytical Methods
- Sample preparation: Solid-phase extraction (water), Soxhlet/accelerated solvent extraction (soil, sediment, dust), solvent extraction/QuEChERS variants (food/oils), thermal desorption or filter extraction (air particulates).
- Separation/detection: GC-FID/GC-MS/GC-MS/MS for non-polar PAHs; HPLC-FLD or LC-MS/MS for isomer-resolved quantification when GC separation is insufficient.
- Isomer separation: PAH-selective GC phases or optimized reversed-phase HPLC gradients to resolve 1-/2-/3-/4-methylpyrene; temperature programs and column selectivity critically influence resolution.
Stable isotope dilution (e.g., deuterated methylpyrene analogs where available, or closely eluting deuterated PAHs) is recommended for compensation of matrix effects and recovery variability.
Sampling and Matrices
Matrices include ambient and workplace air (PM), soils and sediments, stormwater and wastewater effluents, petroleum products, soot/char, and smoked or thermally processed foods (method-dependent). Rigorous contamination control, field blanks, and surrogate spikes are essential due to ubiquitous PAH backgrounds.
Method Validation and QA/QC
- Calibration: Multi-level calibration with matrix-matched or solvent curves using internal standards; verify linearity for each isomer.
- Performance: Determine LOD/LOQ, recovery, precision, and measurement uncertainty for each isomer and matrix; include continuing calibration verification and laboratory control samples.
- Confirmation: Retention time matching, ion ratio criteria (MS), and spectral confirmation or fluorescence ratios (FLD) for isomer specificity.
Human Toxicity
Methylpyrenes share hazard considerations typical of PAHs: they are lipophilic and may undergo metabolic activation to reactive intermediates. Data for individual methylpyrene isomers are more limited than for high-profile PAHs; cautionary handling is advised. Exposure routes include inhalation of particulates/vapors, dermal contact with contaminated oils/soots, and ingestion via contaminated media.
Risk assessment should consider total PAH and alkylated PAH burdens; workplace exposure control follows general PAH hygiene principles in the absence of isomer-specific occupational limits.
Environmental Impact
- Persistence and transport: Strong sorption to sediments and soot; long-range atmospheric transport possible when particle-bound.
- Bioaccumulation: Potential for biota uptake; biotransformation rates vary; alkylated PAHs can persist in petroleum-impacted environments.
- Effects on wildlife: Chronic toxicity potential, especially for early life stages of aquatic organisms; effects depend on mixture composition and exposure conditions.
Site-specific evaluations often include extended PAH homolog series to capture alkylated species such as methylpyrenes in ecological risk assessments.
Safety Measures and Handling
- Controls: Work in a fume hood; avoid aerosol formation; minimize skin contact; use nitrile gloves, lab coat, and eye protection.
- Storage: Keep in amber, tightly sealed containers at 2–8 °C or per product SDS; protect from light; store solutions (e.g., in toluene, iso-octane, or acetonitrile) under inert gas to reduce oxidation/evaporation.
- Spill/Disposal: Absorb with inert material; dispose according to local regulations for PAH-containing organic waste.
Cross-Interferences and Isomer Differentiation
Coelution among alkylated PAHs and matrix hydrocarbons can bias quantification. Use columns with PAH selectivity, optimized temperature programs, and MS/MS transitions or FLD spectral fingerprints. Retention time locking with reference materials and use of deuterated internal standards improve specificity and accuracy.
Reporting and Compliance
- Units: Report in ng/m3 (air), µg/kg (solids/foods), or µg/L (waters); include isomer-specific results where resolved.
- QC documentation: Report recoveries of surrogates, method blanks, uncertainty, and qualifications for non-resolved peaks. Align with project DQOs and regulatory guidance for PAH reporting.
Applications
- Environmental forensics: Source apportionment of petrogenic vs. pyrogenic inputs using methylated/parent PAH ratios.
- Industrial hygiene: Workplace air monitoring near combustion sources, coking, asphalt, and petroleum handling.
- Product stewardship: Characterization of PAH profiles in process streams and materials.
Regulation
While many jurisdictions set limits for selected parent PAHs (e.g., benzo[a]pyrene or PAH4 in foods), methylated PAHs like methylpyrenes may be incorporated into extended monitoring programs, permits, or risk-based site evaluations. Classification and labeling may vary; consult SDS and regional chemical inventories (e.g., EU REACH, CLP) for current status of specific isomers.
Analytical Reference Materials
HPC Standards GmbH supplies high-purity reference materials for methylpyrene isomers to support calibration, system suitability, and QA/QC in GC/LC-based methods. Offerings include neat materials and ready-to-use solutions at application-relevant concentrations, with detailed certificates providing identity, purity, uncertainty, and traceability.
Isotope-labelled derivatives and tailored PAH/methyl-PAH mixes are available to streamline method development and routine monitoring. Our reference materials are tested according to international quality requirements and meet the highest industrial standards.
Why HPC Standards
- Expertise in reference materials for environmental analysis, including PAHs and alkylated PAH homologues.
- Consistent lot-to-lot quality, robust documentation, and technical support for method setup and validation.
- Custom solutions (mix design, solvents, concentrations) to match your regulatory and matrix needs.