Butyric Acid – Reference Materials for Residue and Quality Analysis

Butyric acid High-Purity Reference Materials for Confident Compliance and Precision

Unlock trace-level accuracy with HPC Standards certified butyric acid reference materials. Manufactured under rigorous quality systems and supplied with full documentation CoA, SDS, our neat and ready-to-use solutions support ISOIEC 17025 workflows across food, environmental, air, and process monitoring. Benefit from SI traceability, application-relevant concentrations, isotopically labeled options, and custom blends for VFAs. Rely on rapid lead times, tamper-evident packaging, and ADRIATA-compliant shippingso your lab quantifies with confidence, meets regulatory requirements, and accelerates validation.

Product		Catalog No./ CAS No.	Quantity	Price
Butyric acid		680166 107-92-6	1X1ML	Please log in.
D7-Butyric acid		687511 73607-83-7	1X100MG	Please log in.

HPC Standards GmbH supplies high-purity reference materials for butyric acid to support precise quantification in food, environmental, air, and industrial process monitoring. Our materials are manufactured under strict quality systems, are fully documented, and are optimized for regulatory compliance and accreditation needs.

Overview

Butyric acid (systematic name: butanoic acid) is a short-chain fatty acid (SCFA) widely occurring in dairy products, fermented foods, and anaerobic environments. It is a key odorant with a very low odor threshold and serves as an important quality and process indicator in food production, fermentation, and wastewater treatment.

Chemical identity: C4H8O2; molar mass ~88.11 g/mol; corrosive organic acid with pungent, rancid odor; miscible with many organic solvents and soluble in water. Butyric acid is commonly determined in trace to percent levels across diverse matrices due to its sensory relevance and process diagnostic value.

Chemical and Physical Properties

- Structure: CH3–CH2–CH2–COOH (straight-chain monocarboxylic acid).
- pKa ~4.8 (weak acid; partially dissociated in aqueous media depending on pH).
- Boiling point ~163 °C; density ~0.96 g/mL (20 °C).
- High vapor pressure relative to higher fatty acids; characteristic strong odor; corrosive to skin and eyes.
- Reactivity: typical carboxylic acid chemistry; forms salts (butyrates) and esters; incompatible with strong oxidizers and bases; can corrode some metals.

Uses and Applications

- Food and beverage: flavor component and fermentation marker (dairy, cheese ripening, fermentation control, rancidity/taint assessment).
- Environmental and industrial: indicator of anaerobic degradation, wastewater and sludge monitoring, odor studies, biogas/AD process control.
- Chemical and pharmaceutical: precursor for butyrate salts and esters (e.g., ethyl butyrate), solvent/intermediate roles, research on SCFA biology.

Regulatory Overview

- Classified as a corrosive substance under global GHS systems; transport typically regulated as a corrosive liquid (check current UN classification and packing group before shipment).
- Flavoring substance status and use limits are governed regionally (e.g., EU flavoring regulations, FEMA/GRAS in the US); users must verify applicable local frameworks for intended use.
- Occupational exposure controls may apply in some jurisdictions (facility-specific OELs/WEELs).
- Environmental discharges are regulated under local water, air, and waste statutes due to odor impact and oxygen demand.

Monitoring and Target Matrices

- Food and feed: dairy products, fermented foods, edible oils and fats, flavor formulations, feed and silage.
- Environmental: surface water, wastewater, leachates, sludge, air (odor complaints), soil pore water, biogas plants and digestates.
- Industrial/process: fermentation broths, CIP rinse waters, in-process controls, solvent residues, quality release testing.

Health Impact (Human Toxicity)

- Acute effects: corrosive to skin and eyes; inhalation causes strong respiratory and mucous membrane irritation; ingestion causes gastrointestinal irritation/burns.
- Odor threshold is extremely low; detectable well below irritation thresholds but signifies potential emissions or process deviations.
- Chronic exposure: prolonged contact may cause dermatitis and respiratory irritation; implement exposure controls and hygiene measures.

Environmental Impact

- Readily biodegradable; low potential for bioaccumulation. At elevated concentrations, may exert high biochemical oxygen demand (BOD) and contribute to odor nuisances.
- Effects on wildlife: transient toxicity to aquatic organisms possible at high levels; rapid degradation in receiving waters expected under aerobic conditions.

Safety Measures and Handling

- Use in well-ventilated areas or fume hoods; avoid inhalation of vapors. Wear appropriate PPE: chemical-resistant gloves, goggles/face shield, lab coat; use respiratory protection if ventilation is insufficient.
- Storage: tightly closed, in inert-compatible containers (e.g., glass/PTFE-lined), cool and well-ventilated, away from bases, oxidizers, and reactive metals. Protect from heat and direct sunlight.
- Spill/first aid: neutralize small spills with suitable alkali and absorb; for exposure, rinse affected area with water and seek medical attention according to SDS.

Analytical Methods

- GC-FID/GC-MS: direct analysis of volatile fatty acids using polar columns (e.g., FFAP) or after derivatization (e.g., esterification or silylation) to enhance volatility and detectability.
- Headspace/HS-SPME-GC-MS: effective for trace-level determination and odor investigations in complex matrices.
- HPLC/IC: ion-exclusion or ion chromatography for aqueous matrices; conductivity or UV after derivatization.
- Validation: assess matrix effects, linearity, LOD/LOQ, recovery, repeatability, and measurement uncertainty per ISO/IEC 17025.

Calibration and Quantification

- Use gravimetrically prepared reference materials at multiple levels to establish calibration curves; consider matrix-matched calibration or standard addition for complex samples.
- Isotopically labeled internal standards (e.g., butyric acid-d variants) recommended to correct for volatility, adsorption losses, and matrix effects.
- Routine QC: employ independent check standards, bracketing, and system suitability criteria (retention time windows, resolution, response factors).

Quality, Traceability, and Documentation

- HPC Standards reference materials are manufactured under stringent quality control with full traceability to SI where applicable.
- Each lot is supplied with a Certificate of Analysis detailing identity, purity/assay, uncertainty (k-factor, coverage), preparation scheme, solvent system, and storage conditions.
- Products support ISO/IEC 17025 and ISO 9001-driven quality systems and are aligned with international best practices for measurement assurance.

Product Formats and Customization

- Neat material and ready-to-use solutions (e.g., in methanol, acetonitrile, or water) at application-relevant concentrations.
- Custom blends with related volatile fatty acids or target panels for food, environmental, and odor monitoring programs.
- Isotopically labeled analogues available on request for internal standardization.
- Container options to minimize adsorption and permeation losses; tamper-evident packaging.

Storage and Stability

- Recommended storage: 2–8 °C for solutions unless otherwise stated; protect from moisture and headspace losses; keep tightly sealed.
- Shelf life and assigned stability intervals are lot-specific and indicated on the Certificate of Analysis; observe handling instructions to maintain assigned uncertainty.

Shipping and Compliance

- Shipped according to applicable transport regulations for corrosive substances; temperature-controlled or ADR/IATA-compliant packaging provided as required.
- Accompanying SDS and CoA included; harmonized labeling according to current GHS/CLP.

Related Analytes and Isotopically Labeled Derivatives

- Structural and process-related analytes: isobutyric acid, propionic acid, acetic acid, valeric acids, and characteristic esters (e.g., ethyl butyrate).
- Isotopically labeled derivatives available for robust isotope-dilution quantification.

Frequently Controlled Limits and Guidelines

- Food and flavor quality specifications (internal or buyer-driven) for off-flavor prevention in dairy, beverages, and fats.
- Site-specific odor thresholds and emissions targets for wastewater plants, landfills, and industrial sites.
- Internal action limits in fermentation and biogas processes for process optimization and stability.

Industries Served

- Food and beverage producers, flavor and fragrance manufacturers, contract testing laboratories, environmental monitoring agencies, wastewater and biogas operators, academic and industrial R&D.

Why HPC Standards

- Manufacturer-backed expertise in reference materials for food and environmental analysis, including pesticides, veterinary drugs, metabolites, and isotopically labeled compounds.
- Rapid lead times, application-driven concentrations, and technical support for method development and validation.

Ordering Information

- Provide required concentration, solvent, volume, and any internal standard preferences when requesting a quotation.
- Batch-specific CoA and SDS available prior to purchase; custom concentrations and multi-analyte mixes on request.