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Capstone B — Reference Materials for Residue Analysis
Capstone B reference materials Precision you can trust for compliant residue analysis
Capstone B reference materials from HPC Standards empower your lab to confidently identify and quantify declared actives and key metabolites across water, soil, forage, manure, and compost. Our high-purity neat materials, ready-to-use solutions, and stable isotopelabelled analogues are supplied with comprehensive CoAs to support ISOIEC 17025 workflows and meet EUUS regulatory decision limits. Benefit from matrixmatched calibrators, custom mixes for multi-residue scopes, and expert method support LCMSMS, GCMSMS, SPEQuEChERS. Ensure accuracy, traceability, and auditready resultson time and to the highest industrial standards.
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
ISO 17034 Certified Reference Material Capstone B solution |  | 680800 | 1X10ML | Please log in. |
 | 687493 | 1X25MG | Please log in. | |
 | 693315 | 1X5MG | ||
D6-Capstone B solution |  | 693316 | 1X5ML | Please log in. |
High-quality reference materials for confident identification and quantification of Capstone B actives and related residues in food and environmental matrices.
Overview
Capstone B is a commercial herbicide formulation used for the control of broadleaf and woody vegetation in rangeland, pasture, rights-of-way, and non-crop areas. As a formulated product, its active ingredient composition can vary by market and registration. Laboratories conducting residue analysis typically target the declared active substance(s) and relevant metabolites/degradates specified on the product label and Safety Data Sheet (SDS).
For regulatory monitoring and risk assessment, quantitative determination of the formulation’s active ingredient(s) and key transformation products in environmental (water, soil, sediment) and agricultural (forage, feed, manure, compost) matrices is required.
Uses
Capstone B is applied for vegetation management to suppress or eradicate invasive or undesirable species in grazing land, forestry edges, and industrial sites. Application methods include ground broadcast, spot treatment, and cut-stump or basal treatments per label directions.
Its use pattern influences environmental fate and the selection of target analytes and matrices in surveillance programs (e.g., runoff water post-application, treated pasture forage, adjacent surface waters, or compost/manure streams).
Regulatory
Authorization, use restrictions, and maximum residue limits (MRLs or tolerances) are jurisdiction-specific. Compliance requires analytical methods capable of meeting decision limits at or below the applicable MRLs or environmental quality standards (EQS). Laboratories should reference current national registrations, label stipulations (e.g., grazing and haying restrictions), and any compost/manure management advisories.
Typical compliance frameworks include EU and national regulations for plant protection products, US EPA registrations and tolerances, and water quality criteria where applicable.
Monitoring
Monitoring plans should reflect the product’s label claims and environmental behavior, focusing on:
- Active ingredient(s) declared for Capstone B (per SDS/label)
- Relevant metabolites/degradates known from the literature and regulatory dossiers
- Matrices: surface/ground water, soil, sediment, pasture forage/hay, manure/compost, and biota when required
- Time points: pre-application baseline, post-application intervals (e.g., 1–7 days), and longer-term dissipation studies
Analytical Methods
Choice of method depends on the specific active ingredient(s):
- LC-MS/MS for polar/ionizable herbicide actives and metabolites
- GC-MS/MS for semi-volatile components or derivatized analytes
- SPE or QuEChERS-based extraction with matrix-matched calibration or standard addition in complex matrices
Method validation should address linearity, recovery, matrix effects, precision, trueness, LOQ/LOR, and measurement uncertainty in line with SANTE/12682, ISO/IEC 17025, and ISO 17034 guidance for use of certified reference materials.
Sample Preparation
Representative sampling and prevention of cross-contamination are critical. For water, use amber glass or HDPE with appropriate preservatives and immediate cooling. For soil/plant, homogenize, control moisture, and store at ≤ -18 °C until analysis. Apply SPE/QuEChERS protocols optimized for the target analytes’ polarity and pKa, and include cleanup (e.g., PSA/C18/GCB) as dictated by matrix coextractives.
Quality Assurance and Control
Implement full QC suites: procedural blanks, matrix spikes, matrix-matched calibration, continuing calibration verification, and recovery surrogates. Use isotopically labelled internal standards when available to correct for extraction losses and ion suppression/enhancement.
Health Impact
Human toxicity profiles for Capstone B depend on its active ingredient(s). Risk assessments typically consider acute oral/dermal/inhalation toxicity, skin/eye irritation, sensitization, and systemic effects relevant to operators, workers, bystanders, and consumers. Refer to the product SDS and national assessments for toxicological endpoints and occupational exposure guidance.
Environmental Impact
Environmental fate and ecotoxicity are driven by the actives’ physicochemical properties (e.g., water solubility, pKa, log Kow, Koc) and degradation pathways (hydrolysis, photolysis, biodegradation). Monitoring should address mobility to surface/ground water, persistence in soil/plant matrices, and potential for transfer into manure/compost cycles.
Effects on Wildlife
Potential effects on aquatic organisms, terrestrial plants, pollinators, birds, and soil invertebrates are evaluated in regulatory dossiers. Site-specific risk management (buffer zones, application rate limits, timing restrictions) mitigates exposure.
Safety Measures
Follow label and SDS: appropriate PPE for mixing/loading and application, closed transfer where possible, drift reduction practices, secure storage, and waste handling per local regulations. Laboratories should implement chemical hygiene plans, solvent handling protocols, and decontamination procedures for trace-level work.
Analytical Standards and Reference Materials
HPC Standards provides high-purity reference materials for the active ingredient(s) associated with Capstone B and their key metabolites/degradates. Products are supplied with comprehensive Certificates of Analysis (CoA) including identity confirmation, purity, traceability, and uncertainty data.
- Neat materials and ready-to-use solutions at custom concentrations
- Stable isotope-labelled analogues (where available) for isotope dilution LC-MS/MS
- Matrix-specific calibration solutions on request
All reference materials are produced and tested according to international quality requirements and meet the highest industrial standards to support ISO/IEC 17025 workflows.
Method Development Support
We assist with selection of target analytes, internal standards, and calibration strategies for challenging matrices such as forage, manure, and surface waters. Custom mixtures can be prepared to match your multi-residue scope for Capstone B monitoring.
Storage and Stability
Store reference materials as indicated on the CoA (typically at 2–8 °C for solutions; ambient or refrigerated for sealed neat materials), protected from light and moisture. Observe shelf-life and requalification intervals; equilibrate to room temperature before opening to avoid condensation. Track usage with lot-level documentation for full traceability.
Documentation and Traceability
Each lot is delivered with batch-specific CoA, safety documentation, and recommended handling instructions. Measurement traceability, homogeneity, and stability data ensure reliable quantification and defensible results in audits and regulatory submissions.
Regulation and Compliance Support
Our technical team can align your analytical scope with current regulatory expectations, including target analyte lists, reporting limits, and QC acceptance criteria relevant to Capstone B applications in your jurisdiction.
Ordering Information
Reference materials for Capstone B actives, metabolites, and labelled analogues are available in multiple pack sizes and concentrations. Custom configurations and expedited shipping with temperature control can be arranged to meet project timelines.