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Methoxychlor olefin
Methoxychlor olefin Precision Reference Materials for Confident Residue Analysis
Ensure regulatory-ready results with high-purity Methoxychlor olefin reference materials from HPC Standards. Our neat and solution-grade standards are fully characterized and traceable, optimized for GC-ECDMS workflows, and ideal for calibration, identity confirmation, recovery studies, and impurity profiling. Rely on batch-specific CoA, SDS, and uncertainty data to meet stringent QAQC in food and environmental matrices. Global supply, ISO-aligned quality, and expert technical supportpowering accurate, reproducible quantification.
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
ISO 17034 Reference Material |  | 686495 | 1X10MG | Please log in. |
ISO 17034 Certified Reference Material p,p'-Methoxychlor olefin solution |  | 693509 | 1X1ML | Please log in. |
High-purity reference materials for precise identification and quantification of methoxychlor olefin in food and environmental residue analysis.
Overview
Methoxychlor olefin is a transformation product and technical impurity related to the organochlorine insecticide methoxychlor. It arises primarily via dehydrochlorination of the parent compound and may be encountered in historical pesticide formulations and environmental samples where methoxychlor has been used.
Its physicochemical profile is characterized by low water solubility, high hydrophobicity, and persistence in organic phases, making it relevant for monitoring in soils, sediments, and biota in addition to food/feed matrices subject to legacy contamination.
Chemical Identity and Formation
- Structural class: chlorinated diarylethene (olefin) related to methoxychlor (a DDT analogue with p-methoxy substituents).
- Formation: typically via dehydrochlorination of methoxychlor (e.g., during environmental transformation, storage, or processing), analogous to the DDT → DDE pathway.
- Properties (general): high log Kow, strong sorption to organic matter (high Koc), semi-volatile behavior suitable for GC-based analysis.
Uses and Sources
- Not manufactured for direct application; occurs as a by-product/impurity in technical methoxychlor and as a degradation product in the environment.
- Relevant as a marker of methoxychlor presence, weathering, and product quality control (technical pesticide impurity profiling).
Regulatory Status
- Methoxychlor has been subject to global restrictions and bans; many jurisdictions regulate residues in food and the environment. Methoxychlor olefin may be included in monitoring programs as a related transformation product.
- Specific maximum residue limits (MRLs) for the olefin are uncommon; compliance is typically assessed via parent pesticide regulations, legacy contaminant frameworks, or non-detect policies depending on region. Laboratories should consult current regional legislation and guidance documents.
Monitoring and Target Matrices
- Food and feed: fat-rich commodities (e.g., animal products, oils), plant matrices with historical exposure.
- Environmental: surface water particulates, sediments, soils, sludge, atmospheric particulates, and biota.
- Quality control: impurity profiling of technical-grade methoxychlor and stability studies.
Health Impact – Human Toxicity
- Methoxychlor and several metabolites have been associated with endocrine activity in toxicological literature; methoxychlor olefin is considered in risk assessments as a related compound. Direct toxicological reference values for the olefin may be limited.
- Exposure relevance: primarily via dietary intake of contaminated foods or incidental ingestion/inhalation from contaminated environments. Risk characterization typically follows the parent compound regulatory framework.
Environmental Impact
- Persistence and mobility: favors organic phases; potential for long-range transport via particulate-bound pathways.
- Degradation: slow under environmental conditions; resistant to hydrolysis; photolysis and biotransformation may occur but can be limited in dark, anaerobic, or cold environments.
Effects on Wildlife
- Bioaccumulation potential due to high hydrophobicity; monitoring in aquatic and terrestrial biota may be warranted.
- Ecotoxicological data specific to the olefin may be scarce; assessments often reference organochlorine pesticide class behavior.
Analytical Methods
- Instrumentation: GC-ECD for screening; GC-MS or GC-MS/MS (EI/CI) for confirmation and quantitation. HRMS can support trace-level determination and identity confirmation.
- Analyte behavior: thermally stable under standard GC conditions; non-polar to mid-polar capillary columns commonly used for organochlorines.
- Calibration: multi-level external calibration with matrix-matched standards; use of internal standards (e.g., structural analogues or isotope-labelled surrogates) to correct for recovery and matrix effects.
Sample Preparation
- Food/feed: QuEChERS-based extraction with non-polar clean-up (dispersive PSA/C18 or GPC) for fat-rich samples.
- Environmental: Soxhlet, pressurized liquid extraction (PLE), or ultrasonic extraction followed by silica/alumina or Florisil clean-up; sulfur removal steps may be necessary for sediment.
- Quality controls: method blanks, spikes, matrix duplicates, and continuing calibration verification at relevant LOQs.
Reference Materials from HPC Standards
- Product formats: neat materials and ready-to-use single- and multi-component solutions suitable for GC-based quantification.
- Scope: designed for calibration, system suitability, identity confirmation, recovery studies, and impurity profiling related to methoxychlor.
- Complementary portfolio: reference materials for methoxychlor, related metabolites, and stable isotope-labelled derivatives to support isotope dilution workflows.
Quality and Documentation
- Purity assessment and full characterization according to international quality requirements.
- Documentation provided: Certificate of Analysis (CoA), Safety Data Sheet (SDS), and, where applicable, chromatograms and uncertainty information.
- Traceability: gravimetric preparation with documented balances and reference weights; batch-specific stability and homogeneity checks.
Storage and Stability
- Recommended storage: tightly closed in amber containers at 2–8 °C or frozen (≤ −18 °C) depending on concentration and solvent; protect from light and heat.
- Handling: minimize headspace, use inert gas overlay for neat materials and volatile solutions; record opening dates and maintain usage logs.
- Stability notes: the olefin is generally stable under recommended storage; avoid strong acids/bases and elevated temperatures that may promote further transformation.
Safety Measures and Handling
- Laboratory PPE: lab coat, safety glasses, and suitable chemical-resistant gloves; work in a fume hood.
- Spill and waste: absorb with inert material; dispose of chlorinated organic waste according to local regulations.
- Avoid skin contact, inhalation of vapors/aerosols, and environmental release.
Method Validation and Performance
- Typical performance goals: LOQs in low ng/g (solid matrices) or low ng/L (extracts/clean waters) with recoveries 70–120% and RSD ≤ 20% depending on matrix.
- Use matrix-matched calibration and internal standards to meet identification/confirmation criteria (ion ratios, retention time windows).
Logistics and Supply
- Packaging: flame-sealed ampoules or crimp-cap vials to ensure integrity.
- Shipping: temperature-controlled options available; materials packed to protect from light and mechanical stress.
- Global delivery with batch-specific documentation to support accreditation and routine QA/QC.
Regulatory and Compliance Support
- Alignment with food and environmental testing guidelines; suitable for audit-ready documentation and routine proficiency.
- Technical support for method setup, selection of internal standards, and cross-matrix applicability.