Endrin aldehyde – Reference materials for residue analysis

Endrinaldehyde High-Purity Reference Materials for Confident Residue Analysis

Accelerate reliable quantification with Endrinaldehyde standards from HPC Standards. Our high-purity, CoA-backed reference materials support precise calibration and QC across food, feed, water, soil, sediments, and biota. Manufactured to international quality requirements, they enable robust method validation, regulatory compliance, and routine monitoringalongside tailored mixes Endrin, Endrin aldehyde, Endrin ketone, custom concentrations, and isotope-labelled analogs for isotope dilution. Partner with HPC Standards for consistent results, documented traceability, and expert technical support in food and environmental analysis.

Product		Catalog No./ CAS No.	Quantity	Price
Endrin aldehyde solution Concentration: 100 µg/ml Solvent: Acetonitrile		687618 7421-93-4	1X5ML	Please log in.

High-purity reference materials of Endrin aldehyde for precise quantification in food, feed, water, soil, and biota. Manufactured and tested to international quality requirements for regulatory compliance and method validation.

Overview

Endrin aldehyde is a primary oxidation product and environmental metabolite of the organochlorine insecticide endrin. It is monitored as part of the residue definition for endrin in many jurisdictions due to its persistence, bioaccumulation potential, and toxicity. In analytical control programs, Endrin aldehyde is typically quantified alongside endrin and endrin ketone.

Typical identifiers: synonym “Endrin-aldehyde”; substance class: organochlorine pesticide metabolite; occurrence: degradation/oxidation of endrin in the environment and technical products.

Uses

Industrial or agricultural use of Endrin aldehyde is not intended. Its relevance is analytical: laboratories quantify Endrin aldehyde to assess legacy pesticide contamination, verify remediation success, and ensure food and environmental compliance.

Application areas include: pesticide residue analysis (food and feed), water quality monitoring, soil and sediment assessment, and biomonitoring studies.

Regulatory Status

Endrin (parent compound) is listed for global elimination under international POPs frameworks; consequently, residues of endrin are strictly controlled. Many regulations define residues as the sum of endrin and specific metabolites, including Endrin aldehyde and Endrin ketone, for enforcement.

Typical provisions by region (examples, check current law before reporting):

- Food: default MRLs for non-approved pesticides (often 0.01 mg/kg) or explicit MRLs for the sum of endrin-related compounds depending on commodity and jurisdiction.
- Drinking water: stringent limits for endrin; metabolites may be included in screening and investigative monitoring.
- Environmental quality: monitoring requirements for legacy organochlorines in surface water, sediments, and biota under national and regional programs.

Monitoring and Target Matrices

- Food and feed: high-fat matrices (e.g., fish, dairy, edible oils), cereals, fruits, and vegetables.
- Environmental: surface and groundwater, wastewater, soils, sediments.
- Biota: fish tissue, mussels, and other indicator species for bioaccumulation studies.

Matrix selection is guided by endrin’s legacy use patterns and the persistence of its degradation products.

Human Toxicity

Endrin-class compounds are neurotoxicants affecting the central nervous system. Acute exposure can cause headache, dizziness, nausea, tremors, seizures, and in severe cases respiratory failure. Chronic exposure has been associated with neurological effects and potential hepatic impacts. Endrin aldehyde is considered toxic with hazard concerns similar to the parent compound.

Occupational exposure may occur in legacy contamination scenarios and during analytical handling; strict laboratory safety controls are required.

Environmental Impact

Endrin aldehyde is persistent and hydrophobic with a high potential for sorption to soils and sediments and for bioaccumulation in aquatic and terrestrial food webs. Degradation is slow under environmental conditions, and long-range environmental transport of related organochlorines has been documented.

Effects on Wildlife

Aquatic organisms (fish and invertebrates) are highly sensitive to endrin-related compounds, with acute and chronic toxicity reported at low concentrations. Secondary poisoning of predators is possible due to biomagnification. Protective monitoring is essential near historical application areas and contaminated sediments.

Safety Measures

- Handle solutions and neat materials in a certified chemical fume hood with appropriate PPE (lab coat, nitrile gloves, splash goggles).
- Avoid inhalation, ingestion, and skin contact; prevent environmental release.
- Use dedicated glassware for organochlorines to minimize adsorption losses; prefer solvent-rinsed amber glass vials with PTFE-lined caps.
- Dispose of waste according to local hazardous waste regulations for halogenated organics.

Analytical Methods

- Instrumentation: GC-ECD or GC-MS(/MS) are commonly applied; GC-NCI-MS can enhance selectivity and sensitivity. LC-MS/MS may be used in specific workflows.
- Sample preparation: QuEChERS (with clean-up tailored for non-polar chlorinated analytes), liquid–liquid extraction for water, Soxhlet/pressurized liquid extraction for soil/sediment, and gel permeation chromatography or Florisil/silica clean-up for high-fat matrices.
- Quantification: matrix-matched calibration or isotope dilution when using stable isotope-labelled analogs to correct for matrix effects and recovery variability.
- QA/QC: include procedural blanks, matrix spikes, duplicate samples, and use bracketing calibration with independent check standards.

Method Performance and Validation

Typical LOQs for GC-MS(/MS) in food and water range from low ng/g (µg/kg) to low ng/L depending on matrix and clean-up. Validate linearity, specificity (separation from endrin and endrin ketone), recovery, precision, measurement uncertainty, and analyte stability in extracts according to recognized guidelines (e.g., SANTE/ISO).

Reference Materials

HPC Standards GmbH supplies high-purity reference materials for Endrin aldehyde to support method development, calibration, and quality control. Products are accompanied by a detailed Certificate of Analysis (CoA) specifying purity or assigned concentration, uncertainty, solvent system, and traceability. Stable isotope-labelled derivatives are available for isotope dilution workflows.

Custom concentrations, solvent blends, and multi-analyte mixes (e.g., Endrin, Endrin aldehyde, Endrin ketone) can be provided on request to align with your target methods and matrices.

Storage and Stability

- Store sealed reference materials at 2–8 °C in the dark (amber vials); avoid freeze–thaw cycles.
- Allow equilibrated vials to reach room temperature before opening to prevent condensation.
- Track shelf-life per CoA; monitor working solution stability and re-prepare according to laboratory SOPs.

Quality and Compliance Support

Our reference materials are produced and tested according to international quality requirements and meet high industrial standards. Documentation supports compliance with accreditation frameworks (e.g., ISO/IEC 17025) and regulatory reporting. Technical support is available for selection of compounds, mix design, and implementation in validated methods.

Related Compounds

- Endrin (parent compound)
- Endrin ketone (oxidation product)
- Other legacy organochlorine pesticides relevant for POPs monitoring