New user? / Forgot your password?
0 Item | 0,00 €
Paraquat monopyridone iodide – Reference materials for residue analysis
Paraquat monopyridone iodide HIGH-PURITY Reference Materials for Confident Residue Compliance
Achieve precise, reproducible quantification of paraquat monopyridone iodide across food, feed, water, and environmental matrices. HPC Standards supplies certified reference materialsneat and ready-to-use solutionsmanufactured under ISO-aligned quality controls to support method development, matrix-matched calibration, and routine QC in LCMSMS, HILIC, ion-pair RP-LC, and IC workflows. Benefit from consistent lot quality, documented purity and uncertainty, and optional isotopically labeled internal standards to meet SANTEISO and ISOIEC 17025 requirements. Rely on HPC Standards for robust monitoring of polar pesticideson spec, on time, and ready for regulatory proof.
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 692839 | 1X10MG | ||
D3-Paraquat monopyridone iodide solution |  | 692840 | 1X1ML | |
 | 692837 | 1X10MG | ||
Paraquat monopyridone iodide solution |  | 692838 | 1X1ML |
High-precision reference materials for the determination of paraquat monopyridone iodide in food, feed, water, and environmental samples. Manufactured and quality-controlled to international standards for reliable compliance monitoring.
Overview
Paraquat monopyridone iodide is a cationic bipyridyl-derived salt related to the herbicide paraquat. It is used as a defined analyte or transformation-product analogue in analytical workflows for polar pesticide monitoring. Due to its high polarity and ionic character, dedicated methods and matrix-appropriate calibration are essential for robust quantification.
HPC Standards provides certified reference materials for paraquat monopyridone iodide to support method development, system suitability, calibration, and quality control in routine residue analysis.
Chemical identity and properties
- Structural class: bipyridyl quaternary ammonium derivative (paraquat-related cation) with iodide counterion
- Key characteristics: highly polar, permanently charged; high water solubility; low volatility; light-sensitive
- Analytical behavior: strong cationic retention on mixed-mode/cation-exchange phases; compatible with HILIC, ion-pair RP-LC, IC, and LC–MS/MS
Uses and occurrence
- Analytical use: calibration and QC for targeted quantification of paraquat-related analytes and transformation products in regulatory residue programs
- Occurrence: can be relevant as a monitoring target in studies of paraquat residues and degradation/processing products in plant-derived foods, surface water, and wastewaters
Regulatory status
- Paraquat is banned in the EU and restricted in many jurisdictions; existing MRLs are typically set at or near the analytical LOQ
- Drinking water programs (EU) apply generic pesticide limits (e.g., 0.1 µg/L for single substances); national programs may specify paraquat and related analytes
- Laboratories should consult current regional MRLs, drinking water limits, and environmental quality standards for paraquat and declared metabolites/related ions
Monitoring and target analytes
- Primary targets: paraquat, related bipyridyl cations (e.g., diquat), and paraquat-associated pyridone derivatives where required by scope
- Matrices: high-water foods (fruits/vegetables), grains, teas/herbs, honey, animal products (by exception), drinking and surface water, soil/sediment extracts
- Include isotopically labeled internal standards when available for matrix-compensated quantification
Sample preparation and extraction
- Polar pesticide workflows: QuPPe-type extraction with acidified methanol or acetonitrile/water, followed by cleanup (e.g., PRiME, cation-exchange SPE)
- Water: direct injection or SPE preconcentration using strong cation-exchange cartridges; elution with high-ionic-strength/basic solutions, followed by LC–MS-compatible reconstitution
- Prevent analyte loss by avoiding strongly basic conditions and minimizing light exposure
Analytical methods
- LC–MS/MS: HILIC or ion-pair reversed-phase with volatile counter-ions; MRM transitions optimized for the paraquat-related cation
- Ion chromatography–MS: cation-exchange separation with MS/MS detection
- Typical LOQs: low µg/kg in foods and low ng/L–sub-µg/L in waters, depending on matrix and instrument sensitivity
Quality assurance and calibration
- Use matrix-matched calibration with isotopically labeled internal standards when possible
- Include continuing calibration verification, system suitability checks (retention time, peak shape, response), and laboratory control samples
- Apply recovery correction and uncertainty estimation according to SANTE/ISO guidance
Matrices and reporting limits
- Food: report at or below applicable MRL/LOQ; demonstrate recoveries within acceptance ranges for polar pesticides
- Water: meet regulatory screening levels (e.g., 0.1 µg/L in EU drinking water); validate at relevant LOQs with SPE enrichment where required
Health impact – human toxicity
- Paraquat is highly acutely toxic by ingestion and can cause severe multi-organ injury; respiratory toxicity and pulmonary fibrosis are characteristic of severe exposure
- Low dermal absorption but causes irritation and burns on prolonged contact; eye exposure is hazardous
- Strict laboratory safety controls are required during handling of paraquat-related cations
Environmental impact
- Strong soil adsorption; limited leaching under typical conditions but potential transport via erosion/runoff
- Toxic to non-target plants and aquatic organisms; persistence on mineral surfaces may extend local availability
- Photolysis and oxidative pathways can yield pyridone-type transformation products
Safety measures and handling
- Handle solutions and solids in a fume hood with lab coat, nitrile gloves (double gloving for concentrates), and eye/face protection
- Avoid aerosol formation; prevent contact with skin and eyes; store away from light and incompatible reagents
- Dispose of waste as hazardous according to institutional and legal requirements
Storage and stability
- Store reference materials at 2–8 °C or as specified on the certificate; protect from light and moisture
- Use volumetric solutions within stated validity; monitor for precipitates or discoloration; bring to room temperature before opening
Applications in laboratories
- Development and validation of LC–MS/MS methods for polar pesticides
- Routine monitoring of paraquat-related residues in compliance programs
- Proficiency testing, instrument qualification, and QC trending
Compliance and documentation
- Supplied with certificate including purity, identity confirmation, concentration (for solutions), uncertainty, and traceability
- Manufactured under ISO-aligned quality controls; suitable for ISO/IEC 17025 workflows
Analytical standards and related products
- Paraquat monopyridone iodide reference materials: neat materials and ready-to-use solutions at defined concentrations
- Isotopically labeled internal standards (where available) for paraquat-related analytes
- Companion reference materials: paraquat, diquat, and selected transformation products to support extended monitoring scopes
Why HPC Standards
- Specialized in pesticides, veterinary drugs, metabolites, and stable isotope-labeled derivatives
- Consistent lot-to-lot quality, rapid delivery, and technical support for polar pesticide analytics
- Reference materials designed for stringent regulatory residue analysis in food and environmental matrices