New user? / Forgot your password?
0 Item | 0,00 €
Tetrachlorantraniliprole reference materials
Tetrachlorantraniliprole Reference Materials PRECISION for Confident Compliance
Accelerate your residue analysis with Tetrachlorantraniliprole reference materials from HPC Standards. Our high-purity, CoA-backed standards enable robust method development, calibration, and QC across food and environmental matrices. Manufactured and tested to international quality requirements, they support ISOIEC 17025 workflows with consistent performance, matrix-matched reliability, and traceable documentation. Available as certified neat solids, ready-to-use solution standards, custom mixes, and stable isotopelabelled analoguestailored to your calibration range and regulatory scope. Choose HPC Standards for accuracy, consistency, and expert support in diamide insecticide monitoring.
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
Tetrachlorantraniliprole solution |  | 688319 | 1X1ML | Please log in. |
 | 691332 | 1X10MG | Please log in. |
Precision reference materials for reliable residue analysis in food and environmental matrices. Manufactured and tested to international quality requirements for confident compliance and method validation.
Overview
Tetrachlorantraniliprole is an anthranilic diamide insecticide of the ryanodine receptor modulator class (IRAC Group 28). It is designed to control a broad spectrum of chewing pests in agricultural crops. Due to its potency at low application rates and persistence in certain matrices, robust residue monitoring is essential for regulatory compliance and risk assessment.
HPC Standards GmbH provides Tetrachlorantraniliprole reference materials to support method development, calibration, system suitability, and quality control in accredited laboratories.
Mode of Action
Tetrachlorantraniliprole activates insect ryanodine receptors, causing uncontrolled calcium release in muscle cells, rapid feeding cessation, and death. The compound shows selectivity for insect receptors over mammalian analogs, a hallmark of the diamide class.
Its physicochemical profile supports foliar and, in some programs, soil-directed uses; persistence and partitioning characteristics require tailored analytical extraction and cleanup strategies.
Applications and Uses
- Control of Lepidoptera and certain Coleoptera in fruit, vegetables, specialty crops, and row crops.
- Integrated pest management programs where diamides are rotated with other modes of action to mitigate resistance.
- Residue surveillance in food commodities and environmental monitoring of adjacent compartments (surface water, soils, sediment).
Regulatory Status
Regulatory approval and permitted uses vary by jurisdiction. Authorities typically assess Tetrachlorantraniliprole within the diamide class framework, establishing good agricultural practices (GAP), preharvest intervals, and environmental risk mitigation measures.
Laboratories should consult current national and regional databases (e.g., EU pesticide database, US EPA, Codex Alimentarius) for authorization status, GAP, and associated residue definitions.
Maximum Residue Limits (MRLs)
MRLs or tolerance levels, where established, are commodity-specific and may reference the parent compound and relevant metabolites. Always verify the applicable residue definition and current MRLs for your target market to design appropriate analytical scopes and reportable limits.
Monitoring and Methodology
- Preferred instrumentation: LC-MS/MS (triple quadrupole) with ESI positive or negative depending on mobile phase; HRMS for confirmatory analysis where required.
- Typical workflows: QuEChERS-based extraction (ACN, buffered salts) with d-SPE cleanup; matrix-matched calibration and isotopically corrected quantitation to address matrix effects.
- Confirmation: Multiple MRM transitions, ion ratio verification, and retention time matching to reference materials under the same chromatographic conditions.
Sample Preparation
- Food: QuEChERS (citrate or acetate buffer), PSA/C18/GCB cleanup as matrix dictates; adjust water content for dry commodities.
- Environmental: SPE for water (HLB or mixed-mode), accelerated solvent extraction or ultrasonic extraction for soils/sediments, followed by dispersive or cartridge cleanup.
- Stability: Avoid prolonged exposure to strong acids/bases and high temperatures; assess potential photolysis during handling.
Analytical Targets
Depending on the regulatory residue definition, target the parent Tetrachlorantraniliprole and, where applicable, key transformation products. Stable isotope-labelled analogues are recommended for internal standardization to correct for recovery and matrix suppression/enhancement.
Quality and Accreditation
HPC Standards reference materials are manufactured and tested according to international quality requirements. Each lot is accompanied by a comprehensive Certificate of Analysis (CoA) detailing purity, identity confirmation (LC/GC, MS, NMR where applicable), uncertainty, and storage recommendations.
Storage and Stability
- Store neat materials tightly closed in inert containers at 2–8 °C or as indicated on the CoA.
- Store single- and multi-analyte solutions refrigerated, protected from light. Allow to equilibrate to room temperature before opening to prevent condensation.
- Observe stated expiry and re-test intervals; prepare working dilutions freshly or per validated stability data.
Health Impact – Human Toxicity
Anthranilic diamides generally demonstrate low acute mammalian toxicity relative to their insecticidal potency. Nonetheless, avoid ingestion, inhalation, and skin or eye contact. Potential symptoms of exposure may include mild irritation. Chronic exposure limits and DNELs, where established, should guide risk management in the laboratory.
Always consult the Safety Data Sheet (SDS) for Tetrachlorantraniliprole for detailed toxicological information and first-aid measures.
Occupational Exposure and Safety Measures
- Use in a well-ventilated laboratory, preferably in a fume hood.
- Wear appropriate PPE: lab coat, safety glasses, and chemical-resistant gloves; add respiratory protection if aerosols or solvent vapors may form.
- Implement good laboratory hygiene: avoid food and drink in work areas; wash hands after handling; decontaminate surfaces after use.
Environmental Impact
Tetrachlorantraniliprole is expected to be persistent to moderately persistent in some environmental compartments and may pose risks to aquatic invertebrates. Mobility depends on soil characteristics and formulation. Prevent uncontrolled releases to soil and water.
Risk mitigation typically includes buffer zones and drift/runoff prevention measures in agricultural use; laboratory users should follow waste management best practices.
Effects on Wildlife and Pollinators
As a diamide insecticide, toxicity profiles can vary by species; aquatic invertebrates are generally more sensitive than vertebrates. Effects on pollinators depend on exposure scenario; minimize environmental exposure to protect non-target organisms.
Waste and Spill Management
- Collect spills with inert absorbents; avoid discharge to drains.
- Dispose of waste and contaminated materials via licensed hazardous waste contractors following local regulations.
- Segregate halogenated solvent waste streams where applicable.
Product Formats
HPC Standards offers Tetrachlorantraniliprole reference materials as neat certified solids and ready-to-use solution standards at defined concentrations in high-purity solvents. Custom concentrations, solvent systems, and multi-component mixes are available on request.
Stable isotope-labelled internal standards and selected metabolites can be supplied to support isotope-dilution quantification and confirmatory analysis.
Typical Calibration Ranges
- Food residue analysis: 1–200 µg/L in extract (method LOQs commonly ≤ 5 µg/kg depending on matrix and instrumentation).
- Environmental water: 5–500 ng/L (preconcentration factors may enable sub-ng/L detection by LC-MS/MS or HRMS).
Matrix-matched or standard addition approaches are recommended to compensate for matrix effects.
Matrix Compatibility
Validated across a wide range of matrices including high-water, high-acid, high-fat, and dry commodities, as well as surface water, groundwater, soil, and sediment. Adjust extraction buffers, cleanup sorbents, and dilution factors by matrix to maintain recoveries within 70–120% and RSD ≤ 20% per SANTE/ISO guidance.
Documentation and Compliance Support
Each shipment includes a CoA and SDS. On request, we provide method support notes, uncertainty budgets, and statements of traceability to support ISO/IEC 17025 and ISO 17034-driven quality systems.
Ordering Information
- Available as neat material and as single- or multi-analyte solutions in ACN or MeOH.
- Custom pack sizes and concentrations on request to match your calibration plan and throughput.
Contact HPC Standards for lead times, bulk options, and technical support in selecting the optimal reference materials for your method and regulatory scope.