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CPPD-quinone
CPPD-quinone High-Purity Reference Materials for Confident Residue Analysis
Ensure reproducible, regulation-ready results with HPC Standards high-purity CPPD-quinone reference materials. Designed for food and environmental laboratories, our materials support method development, validation, and routine QCbacked by stringent quality control and comprehensive CoA documentation. Available as neat compounds or ready-to-use solutions, with custom concentrations, mixes, and isotope-labelled analogs on request. Rely on fast delivery, expert technical support, and proven stability to streamline your LCMSMS and LCHRMS workflows and meet international compliance requirements.
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
ISO 17034 Reference Material |  | 691506 | 1X25MG | Please log in. |
ISO 17034 Certified Reference Material CPPD-quinone solution |  | 694405 | 1X1ML | Please log in. |
 | 691131 | 1X5MG | Please log in. | |
ISO 17034 Certified Reference Material D5-CPPD-quinone solution |  | 694419 | 1X1ML | Please log in. |
High-purity reference materials for CPPD-quinone to support accurate residue analysis, method validation, and regulatory compliance in food and environmental laboratories.
Overview
CPPD-quinone is a quinone-type oxidation product belonging to the broader class of redox-active aromatic quinones. Such compounds are electrophilic and can undergo redox cycling and Michael-type addition with nucleophiles (e.g., thiols and amines). In residue and transformation studies, CPPD-quinone may arise as an oxidative metabolite or environmental transformation product of precursor phenolic or aromatic compounds. Its reactivity and potential toxicological relevance make it a target analyte in advanced screening and confirmatory workflows.
Chemical and Analytical Characteristics
- Compound class: aromatic quinone (redox-active, electrophilic)
- Typical behavior: light- and redox-sensitive; can form conjugates with glutathione and proteins; may require antioxidant-free conditions for stability testing
- Chromatographic behavior: amenable to reversed-phase LC; detection by UV (quinone chromophore) and high-sensitivity MS/MS
Uses in Analytical and Research Contexts
- Target/marker analyte in oxidative transformation studies of aromatic precursors
- Reference for method development, validation, and routine QC in food and environmental residue analysis
- Inclusion in suspect/non-target LC–HRMS workflows to document metabolite pathways
Regulatory and Compliance Context
- Laboratories may monitor CPPD-quinone where it is specified as a relevant metabolite or transformation product in regulatory dossiers or internal compliance programs.
- Method validation and quality control should follow internationally recognized guidance (e.g., EU SANTE guidance for pesticide residue analysis in food and feed, or equivalent regional frameworks).
- Substance-specific classification, labeling, and restrictions depend on jurisdiction; consult the Safety Data Sheet (SDS) and local regulations.
Monitoring and Target Matrices
- Food and feed: plant-based matrices where oxidative metabolites are expected during storage/processing
- Environmental: surface water, wastewater, sediments, and soils in transformation/degradation studies
- Laboratory studies: metabolism assays, in vitro oxidation systems, and product stability trials
Analytical Methods
- Sample preparation: protein precipitation or SPE for complex matrices; minimize exposure to light and reducing/oxidizing agents
- Chromatography: HPLC/UPLC reversed-phase; guard against on-column redox artifacts
- Detection: LC–MS/MS (MRM) for selectivity and sensitivity; UV/Vis as secondary detector leveraging quinone absorbance
- Identification/confirmation: retention time match, qualifier transitions/ion ratio criteria, and, where applicable, HRMS exact mass with isotope pattern and fragment confirmation
Human Toxicity and Health Impact
- Quinones are generally associated with redox cycling and oxidative stress; electrophilic reactivity can lead to protein and glutathione adduct formation.
- Potential hazards include skin/eye irritation and sensitization; inhalation or ingestion may cause systemic effects depending on exposure.
- Always refer to the substance-specific SDS for hazard statements, first aid, and occupational exposure guidance.
Environmental Impact and Effects on Wildlife
- Redox-active quinones can contribute to oxidative stress in aquatic and terrestrial organisms.
- Environmental fate is influenced by light, pH, redox conditions, and interactions with natural organic matter; conjugation or reduction to hydroquinone species may occur.
- Perform risk assessments case-by-case; adhere to local discharge and waste-handling regulations.
Safety Measures and Handling
- Use appropriate PPE: lab coat, nitrile gloves, safety glasses; work in a fume hood.
- Avoid contact with skin and eyes; prevent aerosol formation and inhalation of dusts/vapors.
- Protect from light; avoid contact with strong oxidizers/reducers and nucleophilic reagents during handling.
- Dispose of waste according to institutional and regulatory requirements.
Storage and Stability
- Store tightly closed in amber containers at low temperature (e.g., 2–8 °C or frozen), as specified on the CoA/SDS.
- Minimize freeze–thaw cycles; aliquot solutions where possible.
- Use inhibitor-free, HPLC-grade solvents; verify stability in the intended matrix and solvent system.
Quality and Documentation
- Each lot of reference materials is manufactured under stringent quality requirements and supplied with a Certificate of Analysis (CoA) including purity, identity confirmation, and concentration (for solutions).
- Traceability, measurement uncertainty (where applicable), and recommended storage/expiry are documented to support accreditation (e.g., ISO/IEC 17025) and audit needs.
HPC Standards Reference Materials
- Available as neat materials and ready-to-use solutions in suitable solvents (e.g., acetonitrile), delivered in amber ampoules/vials.
- Custom concentrations, mixtures, and matrix-matched solutions available on request to streamline method validation and routine QC.
- Stable isotope-labelled analogs can be offered for isotope-dilution quantification, enhancing accuracy and precision in complex matrices.
Applications in Food and Environmental Analysis
- Confirmation of oxidative metabolites in residue studies of aromatic precursor compounds.
- Inclusion in monitoring lists for transformation product screening in water and soil.
- Process control and proficiency testing support in accredited laboratories.
Ordering Information and Support
- Multiple pack sizes to suit screening, validation, and routine testing volumes.
- Technical support for method setup, stability guidance, and mixture design.
- Rapid delivery with temperature- and light-appropriate packaging to preserve analyte integrity.